Article
Genetic instability in the 9q22.3 region is a late event in the development of squamous cell carcinoma.
Oncogene - 8 Oct 1998
Ahmadian A, Ren Z P, Williams C, Pontén F, Odeberg J, Pontén J, Uhlén M, Lundeberg J
Abstract excerpt
Squamous cell carcinoma (SCC) of the skin represents a group of neoplasms which is associated with exposure to UV light. Recently, we obtained data suggesting that invasive skin cancer and its precursors derive from one original neoplastic clone. Here, the analysis were extended by loss of heterozygosity (LOH) analysis in the chromosome 9q22.3 region. A total of 85 samples, taken from twenty-two sections of...
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