Genetic instability in the 9q22.3 region is a late event in the development of squamous cell carcinoma.

doi:10.1038/sj.onc.1202080

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Article

Genetic instability in the 9q22.3 region is a late event in the development of squamous cell carcinoma.

Oncogene - 8 Oct 1998

Ahmadian A, Ren Z P, Williams C, Pontén F, Odeberg J, Pontén J, Uhlén M, Lundeberg J

Abstract excerpt

Squamous cell carcinoma (SCC) of the skin represents a group of neoplasms which is associated with exposure to UV light. Recently, we obtained data suggesting that invasive skin cancer and its precursors derive from one original neoplastic clone. Here, the analysis were extended by loss of hetero...

Topics

Carcinoma in Situ
Carcinoma, Squamous Cell
Chromosomes, Human, Pair 9
DNA Mutational Analysis
Genes, p53
Humans
Loss of Heterozygosity
Mutation
Skin Neoplasms

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