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Article

Relationship between sunlight exposure and a key genetic alteration in basal cell carcinoma.

Journal of the National Cancer Institute - 20 Mar 1996

Gailani M R, Leffell D J, Ziegler A, Gross E G, Brash D E, Bale A E

Abstract excerpt

BACKGROUND: Basal cell carcinoma (BCC) of the skin is the most common cancer in humans. Epidemiologic studies implicate sunlight exposure as one risk factor, but the limited association between BCCs and UVB radiation (i.e., UV radiation of a wavelength of 280-320 nm) suggests that additional factors must be involved. At the molecular level, not much is known about the role of specific environmental agents in the...

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PMID: 8609643
DOI: 10.1093/jnci/88.6.349

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