Article
Chromosome 9 allele loss occurs in both basal and squamous cell carcinomas of the skin.
The Journal of investigative dermatology - 1 Mar 1994
Quinn A G, Campbell C, Healy E, Rees J L
Abstract excerpt
Linkage studies of kindreds with the nevoid basal cell carcinoma syndrome and the high frequency of chromosome 9 allele loss in sporadic basal cell carcinomas indicate that chromosome 9 may contain tumor suppressor genes important in the development of sporadic and familial basal cell carcinomas. The recent mapping of the Ferguson-Smith syndrome, which predisposes affected individuals to the development of...
Topics
- Alleles
- Carcinoma, Basal Cell
- Carcinoma, Squamous Cell
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 9
- Heterozygote
- Humans
- Skin Neoplasms
