Article
Experimental tumour induction by SV40 transformed cells.
Developments in biological standardization - 1 Jan 1998
Cook J L, Routes B A, Sompayrac L
Abstract excerpt
Although SV40 transforms cells from many species, transformed cells from species other than the Syrian hamster are rarely tumorigenic in immunocompetent animals. However, secondary manipulations of SV40-transformed cells can result in increased tumorigenicity. Some early observations on tumour in...
Topics
- Animals
- Cell Transformation, Neoplastic
- Humans
- Immunity, Cellular
- Models, Biological
- Mutation
- Neoplasms, Experimental
- Phenotype
- Simian virus 40