Article
Experimental tumour induction by SV40 transformed cells.
Developments in biological standardization - 1 Jan 1998
Cook J L, Routes B A, Sompayrac L
Abstract excerpt
Although SV40 transforms cells from many species, transformed cells from species other than the Syrian hamster are rarely tumorigenic in immunocompetent animals. However, secondary manipulations of SV40-transformed cells can result in increased tumorigenicity. Some early observations on tumour induction by SV40 and transformed cells will be followed by a selected review of evidence suggesting that tumorigenicity...
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