Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer

doi:10.1128/cmr.17.3.495-508.2004

Article

Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer

1 Jul 2004

Abstract excerpt

The polyomavirus simian virus 40 (SV40) is a known oncogenic DNA virus which induces primary brain and bone cancers, malignant mesothelioma, and lymphomas in laboratory animals. Persuasive evidence now indicates that SV40 is causing infections in humans today and represents an emerging pathogen. A meta-analysis of molecular, pathological, and clinical data from 1,793 cancer patients indicates that there is a...

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