Transfer of immortality by transfection of genomic DNA from SV40 established cell lines into rat embryo fibroblasts.

doi:10.1016/0248-4900(90)90312-q

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Article

Transfer of immortality by transfection of genomic DNA from SV40 established cell lines into rat embryo fibroblasts.

Biology of the cell - 1 Jan 1990

Jacquemin-Sablon H, Ganz L, Feunteun J

Abstract excerpt

The cellular immortalization activity of cloned genes can be identified either in a colony-forming assa of transfected primary rat embryo fibroblasts or in a co-operation assay together with ras. However the demonstration of immortalization activities carried by cellular genes has not been report...

Topics

Animals
Cell Line
DNA, Viral
Embryo, Mammalian
Fibroblasts
Phenotype
Plasmids
Rats
Rats, Inbred F344
Simian virus 40
Transfection

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