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Article

Transfer of immortality by transfection of genomic DNA from SV40 established cell lines into rat embryo fibroblasts.

Biology of the cell - 1 Jan 1990

Jacquemin-Sablon H, Ganz L, Feunteun J

Abstract excerpt

The cellular immortalization activity of cloned genes can be identified either in a colony-forming assa of transfected primary rat embryo fibroblasts or in a co-operation assay together with ras. However the demonstration of immortalization activities carried by cellular genes has not been reported. Here we establish that SV40 early genes integrated in genomic DNAs can be stably transferred into rat embryo...

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PMID: 2165426
DOI: 10.1016/0248-4900(90)90312-q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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