Article
238Pu alpha-particle-induced C3H10T1/2 transformants are less tumorigenic than the X-ray-induced equivalent.
Carcinogenesis - 1 Jan 1999
Lehane M M, Bryant P E, Riches A C, Allen L A, Briscoe C V, Melville J, Mill A J
Abstract excerpt
Transformation is a complex multistage process in vitro by which benign cells gradually acquire characteristics of tumour cells. Transformed C3H10T1/2 cells appear in vitro as multilayers of cells termed foci. A variety of transformed phenotypes are observed in vitro and in this study samples of these phenotypes were developed as cell lines and assessed for their ability to induce tumours in C3H mice. It was...
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