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Article

Efficient translation of poly(A)-deficient mRNAs in Saccharomyces cerevisiae.

Genes & development - 1 Nov 1994

Proweller A, Butler S

Abstract excerpt

The polyadenylate tail of eukaryotic mRNAs is thought to influence various metabolic phenomena including mRNA stability, translation initiation, and nucleo-cytoplasmic transport. We have analyzed the fate of mRNAs following inactivation of poly(A) polymerase in Saccharomyces cerevisiae containing a temperature-sensitive, lethal mutation (pap1-1) in the gene for poly(A) polymerase (PAP1). Inactivation of poly(A)...

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Identifiers

PMID: 7958921
DOI: 10.1101/gad.8.21.2629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Efficient translation of poly(A)-deficient mRNAs in Saccharomyces cerevisiae.PMID 7958921Read ↗

Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase.Semantic proximity Read ↗

Direct and indirect consequences of <i>PAB1</i> deletion in the regulation of translation initiation, translation termination, and mRNA decaySemantic proximity Read ↗

RNA polymerase III defects suppress a conditional-lethal poly(A) polymerase mutation in Saccharomyces cerevisiae.Semantic proximity Read ↗

A mutation in the tRNA nucleotidyltransferase gene promotes stabilization of mRNAs in Saccharomyces cerevisiae.Semantic proximity Read ↗

Decapping of stabilized, polyadenylated mRNA in yeast pab1 mutants.Semantic proximity Read ↗

Yeast prt1 mutations alter heat-shock gene expression through transcript fragmentation.Semantic proximity Read ↗

Arabidopsis thaliana poly (A) binding protein 2 (PAB2) functions in yeast translational and mRNA decay processes.Semantic proximity Read ↗

Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation.Semantic proximity Read ↗

Tpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae.Semantic proximity Read ↗

In vivo evidence that defects in the transcriptional elongation factors RPB2, TFIIS, and SPT5 enhance upstream poly(A) site utilization.Semantic proximity Read ↗

Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition.Semantic proximity Read ↗

Positive and negative regulation of poly(A) nuclease.Semantic proximity Read ↗

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