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Article

Differential and cooperative polysialylation of the neural cell adhesion molecule by two polysialyltransferases, PST and STX.

The Journal of biological chemistry - 23 Oct 1998

Angata K, Suzuki M, Fukuda M

Abstract excerpt

PST and STX are polysialyltransferases that form polysialic acid in the neural cell adhesion molecule (NCAM), and these two polysialyltransferases often exist together in the same tissues. To determine the individual and combined roles of PST and STX in polysialic acid synthesis, in the present s...

Topics

Animals
CHO Cells
Carbohydrate Sequence
Cricetinae
Glycosylation
Humans
Molecular Sequence Data
Mutation
Neural Cell Adhesion Molecules
Polysaccharides
Protein Processing, Post-Translational
Recombinant Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sialic Acids

Sialyltransferases

Substrate Specificity

Source

Identifiers

PMID: 9774483
DOI: 10.1074/jbc.273.43.28524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9774483-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Differential and cooperative polysialylation of the neural cell adhesion molecule by two polysialyltransferases, PST and STX.PMID 9774483Read ↗

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The polysialyltransferases interact with sequences in two domains of the neural cell adhesion molecule to allow its polysialylation.Semantic proximity Read ↗

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The impact of N-glycosylation on the functions of polysialyltransferases.Semantic proximity Read ↗

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