Association of GAP-43 with detergent-resistant membranes requires two palmitoylated cysteine residues.

doi:10.1074/jbc.273.43.28478

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Article

Association of GAP-43 with detergent-resistant membranes requires two palmitoylated cysteine residues.

The Journal of biological chemistry - 23 Oct 1998

Arni S, Keilbaugh S A, Ostermeyer A G, Brown D A

Abstract excerpt

GAP-43 is an abundant protein in axonal growth cones of developing and regenerating neurons. We found that GAP-43 was enriched in detergent-resistant membranes (DRMs) isolated by Triton X-100 extraction from PC12 pheochromocytoma cells and could be detected in detergent-insoluble plasma membrane...

Topics

Animals
Cell Membrane
Cysteine
Detergents
GAP-43 Protein
GTP-Binding Proteins
Glucosides
Lipoproteins
Mutation
Octoxynol
PC12 Cells
Palmitates
Protein Binding
Protein Processing, Post-Translational
Rats

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