N-terminal cysteines essential for Golgi sorting of B-50 (GAP-43) in PC12 cells.

doi:10.1097/00001756-199505090-00005

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Article

N-terminal cysteines essential for Golgi sorting of B-50 (GAP-43) in PC12 cells.

Neuroreport - 9 May 1995

Aarts L H, van der Linden J A, Hage W J, van Rozen A J, Oestreicher A B, Gispen W H, Schotman P

Abstract excerpt

We have examined the subcellular distribution of the growth-associated protein B-50 (GAP-43) in pheochromocytoma (PC12) cells, using confocal microscopy. Proliferating PC12 cells contained very low levels of B-50 in the cytosol. Enhanced expression of B-50 in these cells, evoked by either nerve growth factor (NGF) treatment or transient transfection with rat B-50 cDNA, led to Golgi sorting and membrane targeting...

Topics

Animals
Base Sequence
Cell Differentiation
Cell Membrane
Cysteine
DNA, Complementary
GAP-43 Protein
Golgi Apparatus
Membrane Glycoproteins
Microscopy, Confocal
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nerve Tissue Proteins

Neurofilament Proteins

Oligonucleotide Probes

PC12 Cells

Rats

Subcellular Fractions

Source

Open in PubMed

Identifiers

PMID: 7632901
DOI: 10.1097/00001756-199505090-00005

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7632901-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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