Article

Peripheral Myelin Protein 22 Preferentially Partitions into Ordered Phase Membrane Domains

2020-01-29

Abstract excerpt

The ordered environment of membrane rafts is thought to exclude many transmembrane proteins. Nevertheless, some multi-pass transmembrane proteins have been proposed to partition into ordered domains. Here, giant plasma membrane vesicles (GPMVs) were employed to quantitatively show that the tetraspan peripheral myelin protein 22 (PMP22) exhibits a pronounced preference for, promotes the formation of, and stabilizes...

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Literature Corpus work: 0ecc128e-98dc-5112-a86a-0e165ac087f2
DOI: 10.1101/2020.01.28.923771

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