Article
Adenylate cyclase in Saccharomyces cerevisiae is a peripheral membrane protein.
Molecular and cellular biology - 1 Aug 1990
Mitts M R, Grant D B, Heideman W
Abstract excerpt
The adenylate cyclase system of the yeast Saccharomyces cerevisiae contains the CYR1 polypeptide, responsible for catalyzing formation of cyclic AMP (cAMP) from ATP, and two RAS polypeptides, which mediate stimulation of cAMP synthesis of guanine nucleotides. By analogy to the mammalian enzyme, models of yeast adenylate cyclase have depicted the enzyme as a membrane protein. We have concluded that adenylate...
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