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Article

Genetic and biochemical analysis of the adenylyl cyclase-associated protein, cap, in Schizosaccharomyces pombe.

Molecular biology of the cell - 1 Feb 1992

Kawamukai M, Gerst J, Field J, Riggs M, Rodgers L, Wigler M, Young D

Abstract excerpt

We have identified, cloned, and studied a gene, cap, encoding a protein that is associated with adenylyl cyclase in the fission yeast Schizosaccharomyces pombe. This protein shares significant sequence homology with the adenylyl cyclase-associated CAP protein in the yeast Saccharomyces cerevisiae. CAP is a bifunctional protein; the N-terminal domain appears to be involved in cellular responsiveness to RAS,...

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Identifiers

PMID: 1550959
DOI: 10.1091/mbc.3.2.167
PMCID: PMC275516

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Genetic and biochemical analysis of the adenylyl cyclase-associated protein, cap, in Schizosaccharomyces pombe.PMID 1550959Read ↗

Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated protein.Semantic proximity Read ↗

Genetic and biochemical analysis of the adenylyl cyclase of Schizosaccharomyces pombe.Semantic proximity Read ↗

Coiled-coil interaction of N-terminal 36 residues of cyclase-associated protein with adenylyl cyclase is sufficient for its function in Saccharomyces cerevisiae ras pathway.Semantic proximity Read ↗

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The Schizosaccharomyces pombe pka1 gene, encoding a homolog of cAMP-dependent protein kinase.Semantic proximity Read ↗

Direct activation of fission yeast adenylate cyclase by the Gpa2 Galpha of the glucose signaling pathway.Semantic proximity Read ↗

Identification of a CAP (adenylyl-cyclase-associated protein) homologous gene in Lentinus edodes and its functional complementation of yeast CAP mutants.Semantic proximity Read ↗

Protein farnesylation is critical for maintaining normal cell morphology and canavanine resistance in Schizosaccharomyces pombe.Semantic proximity Read ↗

Association of yeast adenylyl cyclase with cyclase-associated protein CAP forms a second Ras-binding site which mediates its Ras-dependent activation.Semantic proximity Read ↗

Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Use of PKA-mediated phenotypes for genetic and small-molecule screens in Schizosaccharomyces pombe.Semantic proximity Read ↗

Adenylyl cyclase is dispensable for vegetative cell growth in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

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