Article
Importance of the region around lysine 196 for catalytic activity of adenylyl cyclase from Escherichia coli.
The Journal of biological chemistry - 9 Dec 1994
Amin N, Peterkofsky A
Abstract excerpt
Escherichia coli adenylyl cyclase contains no sequence that corresponds to the previously defined ATP/GTP binding consensus (A,G)XXXXGK(S,T). Using a search for lysine residues located adjacent to glycine residues, three regions that were possible candidates for part of the ATP binding site were...
Topics
- Adenosine Triphosphate
- Adenylyl Cyclases
- Base Sequence
- Catalysis
- Escherichia coli
- Lysine
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Substrate Specificity