Article
G protein beta3 subunit gene variant and blood pressure variation in Canadian Oji-Cree.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 1998
Hegele R A, Harris S B, Hanley A J, Cao H, Zinman B
Abstract excerpt
The subunits of the heterotrimeric G proteins are attractive candidate gene products for both susceptibility to essential hypertension and interindividual variation in blood pressure. There is alternative splicing of exon 9 of the gene encoding the beta3 subunit of heterotrimeric G proteins (GNB3...
Topics
- Adolescent
- Adult
- Analysis of Variance
- Blood Pressure
- Body Mass Index
- Child
- Female
- GTP-Binding Proteins
- Gene Frequency
- Genetic Variation
- Genotype
- Humans
- Hypertension
- Indians, North American
- Linkage Disequilibrium
- Male
- Middle Aged
- Ontario