Article
G-Protein beta3 subunit C825T variant and ambulatory blood pressure in essential hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 1999
Beige J, Hohenbleicher H, Distler A, Sharma A M
Abstract excerpt
Recent studies have identified a novel polymorphism (C825T) of the gene encoding the beta3 subunit of heterotrimeric G proteins (Gbeta3) associated with enhanced activation of G proteins, which appears to be more common in hypertensive patients. In the present study we examine the relationship between this genetic variant and hypertension in 479 white patients with established essential hypertension recruited...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.