Article
The role of G protein β3 subunit polymorphisms C825T, C1429T, and G5177A in Turkish subjects with essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2011
Cabadak Hulya, Orun Oya, Nacar Cevdet, Dogan Yuksel, Guneysel Ozlem, Fak Ali Serdar, Kan Beki
Abstract excerpt
Hypertension is a multifactorial disorder that constitutes a major risk factor for the cardiovascular system. Heterotrimeric G-proteins, which couple receptors for diverse extracellular enzymes or ion channels, are correlated with disease mechanisms. Several studies have demonstrated an association between G protein polymorphisms and essential hypertension in some populations, although contradictive results also...
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