Article
G-protein beta3 subunit gene splice variant and body fat distribution in Nunavut Inuit.
Genome research - 1 Oct 1999
Hegele R A, Anderson C, Young T K, Connelly P W
Abstract excerpt
The GNB3 825T allele encodes a product that has enhanced activation of heterotrimeric G proteins in vitro and could play a role in adipogenesis. We therefore evaluated the possibility that the GNB3 825T allele was associated with obesity in a sample of 213 healthy Canadian Inuit. We found that body weight, body mass index, waist girth, hip girth, subscapular skinfold thickness, and triceps skinfold thickness were...
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