Article
Worldwide ethnic distribution of the G protein beta3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and Black African individuals.
Journal of the American Society of Nephrology : JASN - 1 Sept 1999
Siffert W, Forster P, Jöckel K H, Mvere D A, Brinkmann B, Naber C, Crookes R, Du P Heyns A, Epplen J T, Fridey J, Freedman B I, Müller N, Stolke D, Sharma A M, Al Moutaery K, Grosse-Wilde H, Buerbaum B, Ehrlich T, Ahmad H R, Horsthemke B, Du Toit E D, Tiilikainen A, Ge J, Wang Y, Rosskopf D
Abstract excerpt
Recently, it was demonstrated that one allele (825T) of the gene encoding the G protein beta3 subunit (GNB3) is associated with hypertension in Germans. This study investigates a possible association with obesity in young male Germans, Chinese, and black South Africans with low, intermediate, and high 825T allele frequencies, respectively. In each of these three distinct cohorts, the 825T allele frequency was...
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