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Article

[Suppression of transforming growth factor beta 1 on malignant phenotype in HL-60 cells].

Zhonghua yi xue za zhi - 1 May 1997

Song L, Bai S, Yang W

Abstract excerpt

OBJECTIVE: To study the effect of transforming growth factor beta 1 on tumor cells. METHOD: HL-60 cells were transfected with transforming growth factor beta 1 expression vector by electroporation. Stable cell clones resistant to G 418 were obtained after 2-3 week growth with the drug-containing medium. A series of malignant phenotype were compared between transfected and untransfected HL 60 cells. RESULTS: The...

Topics

Animals
Cell Division
Electroporation
Genes, Tumor Suppressor
HL-60 Cells
Humans
Mice
Mice, Nude
Neoplasm Transplantation
Phenotype
RNA, Messenger
Transfection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transforming Growth Factor beta

Tumor Cells, Cultured

Source

Identifiers

PMID: 9772489

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