Article
[Antisense inhibition of cyclooxygenase-2 reduces malignant phenotype of gastric cancer cells].
Zhonghua nei ke za zhi - 1 Aug 2002
Wu Hanping, Wu Kaichun, Yao Liping, Xu Meihong, Fan Daiming
Abstract excerpt
OBJECTIVE: To investigate the role of cyclooxygenase-2 (COX-2) in tumorigenesis of gastric cancer, and the introduction of into human gastric cancer cells to suppress COX-2 expression. METHODS: The high COX-2 expressing human gastric cancer cell line SGC 7901 was stably transfected with the COX-2 antisense recombinant vector and plain vector (named as 7901-AS and 7901-P cells). The COX-2 expression levels in...
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