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Article

[Reversing malignant phenotypes of liver cancer cell lines with antisense gene to human telomerase reverse transcriptase].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Apr 2002

Yang Shiming, Fang Dianchun, Liu Aimin, Yang Jinliang, Luo Yuanhui, Lu Rong, Liu Weiwen

Abstract excerpt

OBJECTIVE: To explore the effect of antisense gene to human telomerase reverse transcriptase (hTRT) on reversing malignant phenotypes of liver cancer cell lines. METHODS: Sense and antisense eukaryotic expressing vector of hTRT gene was transfected into human liver cancer line HepG(2) with the DOTAP liposomal transfection method. Changes of cellular malignant phenotypes through proliferation capacity, telomerase...

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PMID: 11983122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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