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Article

An experimental study on membrane malignant phenotype of tumour cells and their reversion.

Journal of Tongji Medical University = Tong ji yi ke da xue xue bao - 1 Jan 1994

Yang Y Z, Zhang X H, Zhou R Z, Xia Q S, Liu L, Chen Z C

Abstract excerpt

A human promyelocytic leukemic cell line (HL-60 cells) was induced to differentiate along the myeloid pathway in vitro by 1.25% dimethylsulfoxide (DMSO) as an inducer. The membrane fluidity, the quantity of ConA binding sites on the cell membrane surface, and the protein tyrosine kinase (Tyr-PK) activity existing in NP-40 membrane extract and cytoplasma extract were determined respectively. The activity of...

Topics

Cell Transformation, Neoplastic
Dimethyl Sulfoxide
Female
Humans
Leukemia, Promyelocytic, Acute
Membrane Fluidity
Phenotype
Protein-Tyrosine Kinases
Tumor Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7877199
DOI: 10.1007/BF02888049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7877199-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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