Article
Analyses of mutation and loss of heterozygosity of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human gastric cancer.
Carcinogenesis - 1 Sept 1998
Guo R J, Wang Y, Kaneko E, Wang D Y, Arai H, Hanai H, Takenoshita S, Hagiwara K, Harris C C, Sugimura H
Abstract excerpt
Mutations in the transforming growth factor beta type II receptor (TGFbetaRII) gene have been detected in several human cancer types exhibiting microsatellite instability. Using intron primers previously reported for examination of the entire coding region of the TGFbetaRII gene, 29 sporadic gast...
Topics
- Humans
- Immunohistochemistry
- Loss of Heterozygosity
- Microsatellite Repeats
- Mutation
- Polymorphism, Genetic
- Receptors, Transforming Growth Factor beta
- Stomach Neoplasms