Article
IL1R1 gene polymorphisms are associated with knee osteoarthritis risk in the Chinese Han population.
Oncotarget - 17 Jan 2017
Na Yuyan, Bai Rui, Zhao Zhenqun, Wei Yishan, Li Daihe, Wang Yong, Sun Chao, Sun Liang, Zhang Bolun, Jin Tianbo, Liu Wanlin
Abstract excerpt
IL1R1, encoding interleukin 1 receptor type 1, is located in the IL-1 gene cluster and is involved in the pathogenesis of hand, hip, and knee osteoarthritis (OA) in different ethnicities. However, the link between IL1R1 polymorphisms and OA risk in the Chinese Han population is unknown. We studied the association between five IL1R1 polymorphisms (rs10490571, rs12712127, rs956730, rs3917225, and rs3917318) and OA...
