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Article

The pathway for processing leader-derived peptides that regulate the maturation and expression of Qa-1b.

Immunity - 1 Sept 1998

Bai A, Broen J, Forman J

Abstract excerpt

Qa-1b and its human homolog, HLA-E, predominantly bind leader peptides derived from other class I molecules. Their presentation is TAP-dependent and proteasome-independent. We demonstrate that Dd targeted to the cytosol does not generate the Qa-1b peptide epitope even in the presence of lactacyst...

Topics

Acetylcysteine
Amino Acid Sequence
Animals
Antigen Presentation
Carrier Proteins
Cell Membrane
Cysteine Proteinase Inhibitors
Epitopes
Histocompatibility Antigens Class I
Humans
Mice
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Protein Sorting Signals

T-Lymphocytes, Cytotoxic

Transfection

Tumor Cells, Cultured

Source

Identifiers

PMID: 9768761
DOI: 10.1016/s1074-7613(00)80624-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9768761-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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