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Article

Antigen presentation by MHC class I and CD1 molecules

2009-01-01

Abstract excerpt

Antigen presentation is the ~sine qua non~ of the mammalian adaptive immune system. The assembly of MHC class I/peptide complexes in the endoplasmic reticulum (ER) relies on the orchestrated interplay between different chaperonins, which assist MHC class I folding, and the peptide loading complex (PLC). Mutant lymphoblastoid cell lines with defective MHC class I surface expression have greatly helped the functiona...

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Identifiers and source

Literature Corpus work
f054148f-0bb3-5c6c-8fd8-36075c5db360
DOI
10.21954/ou.ro.0000f26e
Open publication

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Antigen presentation by MHC class I and CD1 moleculesDOI 10.21954/ou.ro.0000f26e
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