Article
Genetic regulation of Dermatophagoides pteronyssinus-specific IgE responsiveness: a genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs. Collaborative Study on the Genetics of Asthma (CSGA).
The Journal of allergy and clinical immunology - 1 Sept 1998
Hizawa N, Freidhoff L R, Chiu Y F, Ehrlich E, Luehr C A, Anderson J L, Duffy D L, Dunston G M, Weber J L, Huang S K, Barnes K C, Marsh D G, Beaty T H
Abstract excerpt
BACKGROUND: Dermatophagoides pteronyssinus (Der p) is one of the most frequently implicated allergens in atopic diseases. Although HLA could play an important role in the development of the IgE response to the Der p allergens, genetic regulation by non-HLA genes influences certain HLA-associated IgE responses to complex allergens. OBJECTIVE: To clarify genetic control for the expression of Der p-specific IgE...
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