Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy.

doi:10.1016/j.jaci.2017.09.015

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy.

The Journal of allergy and clinical immunology - 1 Mar 2018

Asai Yuka, Eslami Aida, van Ginkel C Dorien, Akhabir Loubna, Wan Ming, Ellis George, Ben-Shoshan Moshe, Martino David, Ferreira Manuel A, Allen Katrina, Mazer Bruce, de Groot Hans, de Jong Nicolette W, Gerth van Wijk Roy N, Dubois Anthony E J, Chin Rick, Cheuk Stephen, Hoffman Joshua, Jorgensen Eric, Witte John S, Melles Ronald B, Hong Xiumei, Wang Xiaobin, Hui Jennie, Musk Arthur W Bill, Hunter Michael, James Alan L, Koppelman Gerard H, Sandford Andrew J, Clarke Ann E, Daley Denise

Abstract excerpt

BACKGROUND: Peanut allergy (PA) is a complex disease with both environmental and genetic risk factors. Previously, PA loci were identified in filaggrin (FLG) and HLA in candidate gene studies, and loci in HLA were identified in a genome-wide association study and meta-analysis. OBJECTIVE: We sought to investigate genetic susceptibility to PA. METHODS: Eight hundred fifty cases and 926 hyper-control subjects and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha Catenin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromobox Protein Homolog 5

Share to Epigenesis, Genetic

Share to Filaggrin Proteins

Share to Genetic Loci

Share to Neoplasm Proteins

Share to Phosphoproteins

Share to Repressor Proteins

Source

Open in PubMed

Identifiers

PMID: 29030101
DOI: 10.1016/j.jaci.2017.09.015

Genes

EMSY
ANGPT4
EXOC4
ITGA6
MMP12
MMP13
SKAP1
CTNNA3
ARHGAP24
CBX1
FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy.PMID 29030101Read ↗

Genetics of Food Allergy.Semantic proximity Read ↗

Food Allergy Genetics and Epigenetics: A Review of Genome-Wide Association Studies.Semantic proximity Read ↗

Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.Semantic proximity Read ↗

Update on the genetics of allergic diseases.Semantic proximity Read ↗

Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children.Semantic proximity Read ↗

Current insights into the genetics of food allergy.Semantic proximity Read ↗

Meta-analysis of genome-wide association studies of food allergy and IgE sensitization.Semantic proximity Read ↗

A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.Semantic proximity Read ↗

Application of genetic/genomic approaches to allergic disorders.Semantic proximity Read ↗

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.Semantic proximity Read ↗

The role of genetics in food allergySemantic proximity Read ↗

Genetic determinants of paediatric food allergy: A systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.