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Article

Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria.

The Journal of allergy and clinical immunology - 1 Feb 2024

McSweeney Sheila Mary, Saklatvala Jake, Rispoli Rossella, Ganier Clarisse, Woszczek Grzegorz, Thomas Laurent, Hveem Kristian, Løset Mari, Dand Nick, Tziotzios Christos, Simpson Michael, McGrath John Alexander

Abstract excerpt

BACKGROUND: Urticaria is characterized by inappropriate mast cell degranulation leading to the development of wheals and/or angioedema. Twin and family studies indicate that there is a substantial heritable component to urticaria risk. OBJECTIVE: Our aim was to identify genomic loci at which common genetic variation influences urticaria susceptibility. METHODS: Genome-wide association studies of urticaria...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 37690594
DOI: 10.1016/j.jaci.2023.08.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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