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The genome-wide association study of serum IgE levels demonstrated a shared genetic background in allergic diseases.

Clinical immunology (Orlando, Fla.) - 1 Mar 2024

Lu Hsing-Fang, Chou Chen-Hsing, Lin Ying-Ju, Uchiyama Shunsuke, Terao Chikashi, Wang Yu-Wen, Yang Jai-Sing, Liu Ting-Yuan, Wong Henry Sung-Ching, Chen Sean Chun-Chang, Tsai Fuu-Jen

Abstract excerpt

Immunoglobulin E (IgE) synthessis is highly related to a variety of atopic diseases, and several genome-wide association studies (GWASs) have demonstrated the association between genes and IgE level. In this study, we conducted the largest genome-wide association study of IgE involving a Taiwanese Han population. Eight independent variants exhibited genome-wide significance. Among them, an intronic SNP of CD28,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38199299
DOI: 10.1016/j.clim.2024.109897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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