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Article

An Exploratory Pilot Study of Genetic Marker for IgE-Mediated Allergic Diseases with Expressions of FcεR1α and Cε.

International journal of molecular sciences - 27 Apr 2015

Liao En-Chih, Chang Ching-Yun, Hsieh Chia-Wei, Yu Sheng-Jie, Yin Sui-Chu, Tsai Jaw-Ji

Abstract excerpt

The high affinity immunoglobulin E (IgE) receptor-FcεR1 is mainly expressed on the surface of effector cells. Cross-linking of IgE Abs bound to FcεR1 by multi-valent antigens can induce the activation of these cells and the secretion of inflammatory mediators. Since FcεR1 plays a central role in the induction and maintenance of allergic responses, this study aimed to investigate the association of FcεR1 with the...

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Identifiers

PMID: 25923080
DOI: 10.3390/ijms16059504
PMCID: PMC4463601

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Source receipt: pubmed, retrieved 7 Sept 2026.

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