Article
Investigation of mycobacterial recA function: protein introns in the RecA of pathogenic mycobacteria do not affect competency for homologous recombination.
Molecular microbiology - 1 Sept 1998
Frischkorn K, Sander P, Scholz M, Teschner K, Prammananan T, Böttger E C
Abstract excerpt
The recA locus of pathogenic mycobacteria differs from that of non-pathogenic species in that it contains large intervening sequences termed protein introns or inteins that are excised by an unusual protein-splicing reaction. In addition, a high degree of illegitimate recombination has been obser...
Topics
- Alleles
- Bacterial Proteins
- Blotting, Southern
- Cell Division
- Cloning, Molecular
- Ethyl Methanesulfonate
- Gene Deletion
- Genetic Vectors
- Mitomycin
- Mutagenesis, Insertional
- Mutagens
- Mycobacterium smegmatis
- Mycobacterium tuberculosis
- Phenotype
- Protein Splicing