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Article

Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.

Journal of bacteriology - 1 Jul 2007

Stephanou Nicolas C, Gao Feng, Bongiorno Paola, Ehrt Sabine, Schnappinger Dirk, Shuman Stewart, Glickman Michael S

Abstract excerpt

Bacterial nonhomologous end joining (NHEJ) is a recently described DNA repair pathway best characterized in mycobacteria. Bacterial NHEJ proteins LigD and Ku have been analyzed biochemically, and their roles in linear plasmid repair in vivo have been verified genetically; yet the contributions of NHEJ to repair of chromosomal DNA damage are unknown. Here we use an extensive set of NHEJ- and homologous...

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Identifiers

PMID: 17496093
DOI: 10.1128/JB.00332-07
PMCID: PMC1951864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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