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Article

Modulating cellular recombination potential through alterations in RecA structure and regulation.

Molecular microbiology - 1 Dec 2010

Bakhlanova Irina V, Dudkina Alexandra V, Baitin Dima M, Knight Kendall L, Cox Michael M, Lanzov Vladislav A

Abstract excerpt

The wild-type Escherichia coli RecA protein is a recombinase platform with unrealized recombination potential. We have explored the factors affecting recombination during conjugation with a quantitative assay. Regulatory proteins that affect RecA function have the capacity to increase or decrease recombination frequencies by factors up to sixfold. Autoinhibition by the RecA C-terminus can affect recombination...

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Source

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Identifiers

PMID: 21143322
DOI: 10.1111/j.1365-2958.2010.07424.x
PMCID: PMC3059143

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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