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Mycobacterium bovis BCG moreau is naturally deficient in homologous recombination.

Tuberculosis (Edinburgh, Scotland) - 1 Jul 2020

Schwarz Marcos Gustavo Araujo, Corrêa Paloma Rezende, Malaga Wladimir, Guilhot Christophe, Mendonça-Lima Leila

Abstract excerpt

The ability to perform genetic manipulation of mycobacteria is important for characterization of gene function. Homologous recombination-based protocols are frequently used for reverse genetics studies with mycobacteria. It is known that Mycobacteriumbovis BCG Russia, closely related to M. bovis BCG Moreau, is a natural recA deficient strain and is non-permissive to homologous recombination assays. In this work...

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PMID: 32741533
DOI: 10.1016/j.tube.2020.101956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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