Article
Analysis of cytochrome P450 2E1 genetic polymorphisms in relation to human lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 1994
Kato S, Shields P G, Caporaso N E, Sugimura H, Trivers G E, Tucker M A, Trump B F, Weston A, Harris C C
Abstract excerpt
Human cancer risk assessment using molecular genetic techniques is a rapidly emerging field. Many studies suggest that both inherited and acquired genetic predispositions play an important role in carcinogenesis. Cytochrome P450 (CYP) 2E1 is involved in the metabolic activation of N-nitrosamines...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Asian People
- Black People
- Case-Control Studies
- Cytochrome P-450 CYP2E1
- Cytochrome P-450 Enzyme System
- Female
- Gene Amplification
- Gene Frequency
- Genotype
- Haplotypes
- Humans
- Introns
- Japan
- Lung Neoplasms
- Male