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Article

Clonal evolution of B cells in transformation from low- to high-grade lymphoma.

European journal of immunology - 1 Apr 1999

Matolcsy A, Schattner E J, Knowles D M, Casali P

Abstract excerpt

An outcome of low-grade B cell non-Hodgkins's lymphomas is the transformation to high-grade diffuse large B cell lymphomas (DLBL). To investigate the mechanisms of clonal evolution in the transformation to DLBL, we performed longitudinal molecular analyses of immunoglobulin (Ig), V(H)DJ(H) gene sequences expressed in cases of chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and follicular...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10229093
DOI: 10.1002/(SICI)1521-4141(199904)29:04<1253::AID-IMMU1253>3.0.CO;2-8
PMCID: PMC4625534

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Source receipt: pubmed, retrieved 7 Sept 2026.

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