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Article

Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice.

Arthritis and rheumatism - 1 Sept 1998

Mohan C, Morel L, Yang P, Wakeland E K

Abstract excerpt

OBJECTIVE: In order to shed light on the role of splenic B1 cells in disease pathogenesis in lupus-prone mice, this study was undertaken to determine how efficiently these cells can serve as antigen-presenting cells (APC) and to ascertain which murine lupus susceptibility loci dictate the expansion of these cells. METHODS: Spleens and peritoneal cavities (PerC) of NZM2410 lupus-prone mice, as well as of control...

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PMID: 9751099
DOI: 10.1002/1529-0131(199809)41:9<1652::AID-ART17>3.0.CO;2-W

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APC

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