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Article

Mechanisms of peritoneal B-1a cells accumulation induced by murine lupus susceptibility locus Sle2.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2004

Xu Zhiwei, Butfiloski Edward J, Sobel Eric S, Morel Laurence

Abstract excerpt

The abundance of B-1a cells found in the peritoneal cavity of mice is under genetic control. The lupus-prone mouse New Zealand Black and New Zealand White (NZB x NZW)F(1) and its derivative NZM2410 are among the strains with the highest numbers of peritoneal B1-a cells. We have previously identified an NZM2410 genetic locus, Sle2, which is associated with the production of large numbers of B-1a cells. In this...

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PMID: 15528340
DOI: 10.4049/jimmunol.173.10.6050

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Mechanisms of peritoneal B-1a cells accumulation induced by murine lupus susceptibility locus Sle2.PMID 15528340Read ↗

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