Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

1 Nov 2015

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical and immunological manifestations. Several spontaneous and inducible animal models mirror common components of human disease, including the bm12 transfer model. Upon transfer of bm12 splenocytes or purified CD4 T cells, C57BL/6 mice rapidly develop large frequencies of T follicular helper cells (Tfh), germinal center (GC) B cells,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Systemic Lupus Erythematosus Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26554458
DOI: 10.3791/53319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 MicePMID 26554458Read ↗

Assessing the Molecular Validity of Spontaneous Lupus Mouse Models and Its Implication for Human StudiesSemantic proximity Read ↗

A new site-directed transgenic rheumatoid factor mouse model demonstrates extrafollicular class switch and plasmablast formationSemantic proximity Read ↗

Animal Models of Lupus and Lupus NephritisSemantic proximity Read ↗

Induced murine models of systemic lupus erythematosus.Semantic proximity Read ↗

The IL‐12‐STAT4 axis in the pathogenesis of human systemic lupus erythematosusSemantic proximity Read ↗

Murine models of systemic lupus erythematosus.Semantic proximity Read ↗

Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice.Semantic proximity Read ↗

Contribution of mouse models in our understanding of lupusSemantic proximity Read ↗

Lowering CD40L expression in Murine Lupus Results in an Increase in Disease Indicators in Female but not Male B6 miceSemantic proximity Read ↗

B cells expressing the transcription factor T-bet drive lupus-like autoimmunitySemantic proximity Read ↗

B10 Cells: A Functionally Defined Regulatory B Cell SubsetSemantic proximity Read ↗

CD8 T lymphocytes infiltrate the kidneys and correlate with disease progression in B6. <i>NZMSle1/Sle2/Sle3</i> lupus miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.