Article
Translational regulation of hepatitis B virus polymerase gene by termination-reinitiation of an upstream minicistron in a length-dependent manner.
The Journal of general virology - 1 Sept 1998
Hwang W L, Su T S
Abstract excerpt
Hepatitis B virus (HBV) polymerase (P) gene is translated from the bicistronic pregenomic RNA with the core (C) gene in the first cistron. The P ORF is preceded by the C AUG and three AUG codons within the C region, where a minicistron of 7 amino acids can potentially be translated. Our results i...
Topics
- Amino Acid Sequence
- Artificial Gene Fusion
- Base Sequence
- Cell Line
- Gene Expression Regulation, Viral
- Gene Products, pol
- Genes
- Genes, Reporter
- Genes, Viral
- Hepatitis B virus
- Humans
- Lac Operon
- Mutation
- Peptide Chain Termination, Translational
- Plasmids
- Protein Biosynthesis
- RNA-Directed DNA Polymerase
- Ribosomes
