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Article

Mechanism of translation of the hepadnaviral polymerase (P) gene.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990

Chang L J, Ganem D, Varmus H E

Abstract excerpt

Unlike many other reverse transcriptase genes, the polymerase (P) gene of the hepatitis B viruses is expressed by translational initiation from its own AUG codon rather than by ribosomal frameshifting during translation of the overlapping core gene (C). To explore the mechanism of its translation, we have fused the P gene of duck hepatitis B virus to the bacterial lacZ gene at a point 3' to the C-P overlap; this...

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Identifiers

PMID: 1695011
DOI: 10.1073/pnas.87.13.5158
PMCID: PMC54281

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