A cis-acting element within the hepatitis A virus 5'-non-coding region required for in vitro translation.

doi:10.1016/0168-1702(92)90143-w

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Article

A cis-acting element within the hepatitis A virus 5'-non-coding region required for in vitro translation.

Virus research - 1 Oct 1992

Glass M J, Summers D F

Abstract excerpt

Every picornavirus studied thus far has a sequence within the 5'-non-coding region that is required for internal ribosome binding and translation of the polyprotein. In an attempt to identify this region in hepatitis A virus we constructed a truncated hepatitis A virus (HAV) cDNA clone that conta...

Topics

Base Sequence
Capsid
Cell-Free System
Codon
DNA
Genome, Viral
Hepatovirus
Molecular Sequence Data
Mutation
Protein Biosynthesis
RNA Caps
RNA, Viral
Sequence Analysis, RNA
Transcription, Genetic

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