Article
Patterns of reticulate evolution for the classical class I and II HLA loci.
Immunogenetics - 1 Oct 1998
Jakobsen I B, Wilson S R, Easteal S
Abstract excerpt
Some alleles of the major histocompatibility complex (MHC) genes have a reticulate pattern of evolution, probably resulting from the exchange of segments by gene conversion or recombination. Here we compare the extent and patterns of reticulate evolution among the classical class I and class II l...
Topics
- Alleles
- Computational Biology
- Evolution, Molecular
- Gene Conversion
- Genes, MHC Class I
- HLA-D Antigens
- Humans
- Recombination, Genetic
- Sequence Homology, Amino Acid