Evolution of MHC IIB Diversity Across Cichlid Fish Radiations.

doi:10.1093/gbe/evad110

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Article

Evolution of MHC IIB Diversity Across Cichlid Fish Radiations.

Genome biology and evolution - 1 Jun 2023

Lozano-Martín Carlos, Bracamonte Seraina E, Barluenga Marta

Abstract excerpt

The genes of the major histocompatibility complex (MHC) are among the most polymorphic genes in vertebrates and crucial for their adaptive immune response. These genes frequently show inconsistencies between allelic genealogies and species phylogenies. This phenomenon is thought to be the result of parasite-mediated balancing selection maintaining ancient alleles through speciation events (trans-species...

Topics

Animals
Cichlids
Major Histocompatibility Complex
Polymorphism, Genetic
Histocompatibility Antigens Class II
Phylogeny
Alleles
Genes, MHC Class II
Selection, Genetic

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Identifiers

PMID: 37314153
DOI: 10.1093/gbe/evad110
PMCID: PMC10306275

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