Article
Polymorphism of the IL-1 gene complex in Epstein-Barr virus seronegative and seropositive adult blood donors.
Scandinavian journal of immunology - 1 Sept 1998
Hurme M, Helminen M
Abstract excerpt
Epstein-Barr virus (EBV) seronegativity is rare in adults. To examine whether genetic differences would explain this, we studied the genetic polymorphisms of the genes of the interleukin-1 (IL-1) complex in seronegative adults. These cytokines (i.e. IL-1alpha, IL-1beta and IL-1 receptor antagonist, IL-1RA) regulate, in several ways, the inflammatory reactions of the body. In each of these genes there are...
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