Article
Exhaustive genotyping of the interleukin-1 family genes and associations with AIDS progression in a French cohort.
The Journal of infectious diseases - 1 Dec 2006
Do Herve, Vasilescu Alexandre, Carpentier Wassila, Meyer Laurence, Diop Gora, Hirtzig Thomas, Coulonges Cedric, Labib Taoufik, Spadoni Jean-Louis, Therwath Amu, Lathrop Mark, Matsuda Fumihiko, Zagury Jean-Francois
Abstract excerpt
Interleukin (IL)-1 family members are key players in inflammatory processes but have been the subject of few studies of acquired immunodeficiency syndrome (AIDS). To better evaluate the impact of the IL-1 family on AIDS development, we genotyped the IL1 alpha , IL1 beta , IL1Ra, and IL1R1 genes in 245 slow progressor (SP) and 82 rapid progressor (RP) human immunodeficiency virus type 1-seropositive patients as...
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