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Article

Non-melanoma skin cancer in mouse and man.

Archives of toxicology - 1 May 2013

Schwarz Michael, Münzel Peter A, Braeuning Albert

Abstract excerpt

As a frontier organ, skin is exposed to different environmental and/or occupational chemicals which cause cutaneous cancers in experimental animals. In mice, 7,12-dimethylbenz[a]anthrancene (DMBA) and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) are frequently used as skin model tumor initiator and promoter, respectively. The sequential administration of DMBA and TPA leads to the appearance of a...

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Identifiers

PMID: 23266722
DOI: 10.1007/s00204-012-0998-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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